The effect of baseline knee pain on knee joint cartilage loss in anterior cruciate ligament reconstructed individuals: A target trial emulation based on the MIRAKOS cohort study.
ONGOING PROJECTS
Physiotherapy and Biomechanics Research Unit
The Parker Institute has recently initiated the CANO project titled: "High-Intensity Cardiovascular Training and Biomechanical Neuromuscular Training as Treatment for Knee Osteoarthritis: A Randomized Study."
In brief, the project aims to investigate the physiological benefits of engaging in training 2-3 times a week for 8-12 weeks for individuals with knee osteoarthritis who also suffer from one or more cardiovascular risk factors such as high BMI, elevated blood pressure, increased blood sugar, and high cholesterol.
The project is spearheaded by Professor Marius Henriksen and Postdoc Cecilie Bartholdy.
Supported by Sygeforsikring ”danmark” and The Oak Foundation, we are currently seeking potential trial participants. If you are interested in learning more or participating, please feel free to email Ph.D. student Mathilde Espe Pedersen at mathilde.espe.pedersen.01@regionh.dk along with your phone number. A project staff member will then contact you as soon as possible.
Imaging Unit
Investigators
Elisabeth Bandak, Marius Henriksen, Mikael Boesen
Summary
In patients with knee OA retrospective data on Dynamic Contrast Enhanced MRI (DCE-MRI) of the thigh and knee, systemic markers (blood samples, synovial fluids), assessments of mobility (muscle strength, Six-minute walk test, and biomechanical gait analysis) will be analyzed. Further, patient reported outcomes on pain, symptoms, and physical function in patients is acquired using questionnaires are available and will be included in the analyses.